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Note: The Tampa Bay-Las Vegas game originally scheduled for Sunday night has been moved and is currently scheduled in the 4 p.m. window. In a corresponding move, the Seattle-Arizona game has been moved to Sunday night.
1 p.m. ET games
Offense
John Brown, WR, BUF: Knee — OUT
Impact: Gabriel Davis will fill in for Brown and could deliver some value.
Dawson Knox, TE, BUF: Calf — OUT/IR
Impact: Tyler Kroft can play, but Lee Smith must also sit as a result of Knox’s positive COVID-19 test.
Curtis Samuel, WR, CAR: Knee — Questionable
Impact: Keith Kirkwood will likely start in his stead, as he did last week.
Joe Mixon, RB, CIN: Foot — OUT
Impact: Giovani Bernard could return huge value as he takes over the majority of Mixon’s workload.
John Ross III, WR, CIN: Illness — Questionable
Impact: There’s just no value here, as Tee Higgins has stepped up big time.
Austin Hooper, TE, CLE: Appendix — OUT
Impact: David Njoku and Harrison Bryant will split time in an effort to replace the ill tight end.
Aaron Jones, RB, GB: Calf — Questionable
Impact: Jamaal Williams is ready to have a huge day. All signs point to Jones sitting this one out.
Robert Tonyan, TE, GB: Ankle — Questionable
Impact: Marcedes Lewis/Jace Sternberger are potential replacements if Tonyan can’t go.
Michael Thomas, WR, NO: Hamstring — OUT
Impact: Tre’Quan Smith, Marquez Callaway and Deonte Harris are all the WRs that Drew Brees has to throw to this week.
Sam Darnold, QB, NYJ: Shoulder — Questionable
Impact: Expected to return, barring any weekend setbacks.
Jamison Crowder, WR, NYJ: Groin — Doubtful
Impact: Denzel Mims was activated from IR and could see some extra targets.
Sam Ficken, K, NYJ: Groin — Doubtful
Impact: Sergio Castillo, recently signed to the practice squad, would be the team’s emergency option.
Antonio Gandy-Golden, WR, WSH: Hamstring — OUT
Impact: Dontrelle Inman should see a significant bump in value.
Isaiah Wright, WR, WSH: Shoulder — OUT
Impact: Cam Sims and Robert Foster might enter the WR mix.
Defense
Takkarist McKinley, DE, ATL: Groin — Questionable
Matt Milano, LB, BUF: Pectoral — Questionable
Josh Norman, CB, BUF: Hamstring — OUT
Tre’Davious White, CB, BUF: Back — Questionable
Eli Apple, CB, CAR: Hamstring — Questionable
Donte Jackson, CB, CAR: Toe — Questionable
William Jackson III, CB, CIN: Concussion — OUT
Karl Joseph, S, CLE: Hamstring — Questionable
Tyler Lancaster, DE, GB: Shoulder — OUT
Preston Smith, LB, GB: Shoulder — Questionable
Kevin King, CB, GB: Quad — Doubtful
Darnell Savage Jr., S, GB: Quad — Doubtful
Mike Hilton, CB, PIT: Shoulder — OUT
4 p.m. ET games
Offense
Tyler Eifert, TE, JAX: Neck — OUT
Impact: James O’Shaughnessy didn’t do much when he filled in after Eifert’s injury last week.
Chris Thompson, RB, JAX: Illness — OUT/IR
Impact: He has been placed on the reserve/COVID-19 list. His limited fantasy value may be usurped by Devine Ozigbo, just off the IR.
Sammy Watkins, WR, KC: Hamstring — OUT
Impact: Demarcus Robinson and Mecole Hardman both see increased fantasy value.
Tyrod Taylor, QB, LAC: Chest — Questionable
Impact: Justin Herbert has been strong since taking over for Taylor, who might not start again this season, even when 100% healthy.
Justin Jackson, RB, LAC: Knee — Questionable
Impact: Expected to play and should see more work than Joshua Kelley.
KJ Hill Jr., WR, LAC: Hip — Questionable
Impact: Just as well if he sits, as Keenan Allen appears to be at full strength.
Bryan Edwards, WR, LV: Ankle — OUT
Impact: Hasn’t been ready for a month now, which means job security for the trio of Henry Ruggs III, Nelson Agholor and Hunter Renfrow.
Julian Edelman, WR, NE: Knee — Questionable
Impact: What else is new? Edelman is questionable. Edelman will almost certainly play.
Raheem Mostert, RB, SF: Ankle — OUT/IR
Impact: JaMycal Hasty and Jerick McKinnon will split RB duties …
Jeff Wilson Jr., RB, SF: Calf — Questionable
Impact: … with Tevin Coleman possibly rejoining the team next week.
Defense
Jeremiah Attaochu, DE, DEN: Quad — OUT
Myles Jack, LB, JAX: Ankle — OUT
Maliek Collins, DT, LV: Shoulder — Questionable
Adam Butler, DT, NE: Elbow — Questionable
Kwon Alexander, LB, SF: Ankle — OUT
Jimmie Ward, S, SF: Quad — OUT
Jaquiski Tartt, S, SF: Groin — OUT
Sunday night game
Seattle Seahawks
Jamal Adams, S: Groin — OUT
Arizona Cardinals
DeAndre Hopkins, WR: Ankle — Questionable
Impact: Late-week practice, albeit of a limited nature, does point to Hopkins being able to go on Sunday night.
Jordan Phillips, DE: Foot — Questionable
Kylie Fitts, LB: Hamstring — Questionable
Dre Kirkpatrick, CB: Foot — Questionable
Official Sunday inactives should begin coming in at approximately 11:30 a.m. ET for the early games and 2:30 p.m. ET for the late games.
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