German pharmaceutical giant Merck and a US partner reported promising results Saturday in trials of a drug administered orally to fight Covid-19, saying it helps reduce patients’ viral load.
“At a time where there is unmet need for antiviral treatments against SARS-CoV-2, we are encouraged by these preliminary data,” said Wendy Painter, chief medical officer of the US firm, Ridgeback Biotherapeutics.
This drug caused a significant drop in patients’ viral load after five days of treatment with it, Merck said at a meeting with infectious disease experts.
No safety alert
There was no alert in terms of safety, and of four serious adverse events that were reported, none were considered to be related to taking this drug, Ridgeback said.
Anti-viral oral drugs such as oseltamivir (Tamiflu) and zanamivir (Relenza) are sometimes prescribed for seasonal flu but researchers have yet to come up with something similar to fight the coronavirus.
The findings of this study — a quicker decrease in viral load among individuals with early-stage Covid-19 who are treated with molnupiravir — are promising, said William Fischer, lead investigator of the study and a professor of medicine at the University of North Carolina.
Merck is also working on another oral Covid treatment called MK-711.
Preliminary results from clinical trials with it show a more than 50 per cent reduction in risk of death or respiratory trouble in patients hospitalised with moderate to severe Covid-19, the company said in January.
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